The Complete Solution for Medical Necessity

Proactive, automated medical necessity handling, from pre-visit reviews to denied claim appeals
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Substrate puts medical necessity on autopilot, so you can go back to caring for patients,
Enhanced medical record & prior authorization review
Substrate AI agents review and compare all the relevant documents to validate medical necessity. We automatically ingest your medical records and prior auths, and use AI to read and compare them to ensure that the right care was provided to the right patient by the right provider, the correct dX codes were present, and the procedures were appropriately authorized.
Hands-free appeal submission for pended and denied claims
Once validated, our AI agents automatically generate and submit appeals for you via the payor portals or via fax. All you have to do is review, and hit send.
Proactive prior authorization monitoring & alerts
Substrate's AI agents proactively monitor your daily appointment roster to ensure that any visits which require a prior authorization have one on file. We also notify you when a visit is not authorized or when a prior authorization is about to expire.
Automatic Claims Status
The Substrate platform can automatically check claims status for you on a daily basis to track and respond to claims the day they are denied or pended.
Easy integration
Works with any EMR or practice management system, with all information synchronized to your existing wordlist and queues. No IT or engineering team work is required.

About Medical Necessity Denials

Payers often reject claims because their systems or staff believe the care provided was not medically necessary. Different payers use several different denial and CARC & RARC codes to indicate medical necessity, and will often request medical records, proof of prior authorization, or both to be submitted. These documents are tedious to get, time consuming to validate, and cannot be automatically submitted.

Substrate makes it possible to automate the process of detecting, validating and submitting medical records or prior authorization documents without human intervention. Substrate also detects medical records requests while they're still pending and appeals them automatically before you get a denial, and tracks visits requiring prior authorization so you prevent a medical necessity denial, as well as tracks appeals so you can tell if you got paid, or see trends in real time. Some sample denial , CARC, RARC, or Closure codes are below:

  • Code: 7Y
    Payer: United Health Care / Optum
    Type: Closure Code

    LETTER IS BEING SENT. PLEASE REFER TO THE DETAIL LETTER DESCRIPTION LISTED ON THE SECONDARY LINE LEVEL CODE (LISTED JUST BELOW). ADDITIONAL INFORMATION CAN BE SUBMITTED ELECTRONICALLY BY SCROLLING TO THE BOTTOM OF THIS PAGE AND CLICKING ON VIEW OR TAKE ACTION ON YOUR CLAIM AND THEN CLICK ON ADD ATTACHMENTS.

  • Code: FQ
    Payer: United Health Care / Optum
    Type:  Closure Code

    THE CLAIM OR ENCOUNTER IS WAITING FOR INFORMATION THAT HAS ALREADY BEEN REQUESTED FROM THE PROVIDER. MEDICAL NOTE/REPORT.

  • Code: 252
    Payer: United Health Care / Optum
    Type: Claim Adjustment Reason Code (CARC)

    AN ATTACHMENT/OTHER DOCUMENTATION IS REQUIRED TO ADJUDICATE THIS CLAIM/SERVICE.

  • Code: N683
    Payer: United Health Care / Optum
    Type: Remittance Advice Remark Code (RARC)

    MISSING/INCOMPLETE/INVALID PRIOR TREATMENT DOCUMENTATION

  • Code: 360
    Payer: Blue Cross Blue Shield
    Type: Claim Adjustment Reason Code (CARC)

    A letter has been mailed detailing additional information required to review prior to processing this claim. Submit the requested records.

Several clinical specialties struggle with medical necessity denials

If your practice experiences a high frequency of medical necessity denials, then Substrate is right for you. Some example specialities we work with (and the procedure codes they experience medical necessity denials for) are below.

  • Physical Therapy & Rehabilitation


    - CPT 97110 – Therapeutic exercises to develop strength/endurance, range of motion, and flexibility
    - Why It May Be Denied
    : Payers may determine ongoing or repeated sessions are not medically necessary (e.g., maintenance therapy rather than rehabilitative therapy) or request more rigorous documentation of functional improvement.

    - CPT 97112 – Neuromuscular reeducation of movement, balance, coordination, kinesthetic sense, posture, and proprioception
    - Why It May Be Denied
    : Insufficient documentation showing the need for skilled therapy or lack of measurable progress toward treatment goals.

  • Orthopedic Surgery


    - CPT 27447 – Arthroplasty, knee, condyle and plateau; medial and lateral compartments with or without patella resurfacing (total knee replacement)
    - Why It May Be Denied
    : Denials can occur if there is inadequate evidence of conservative treatment failure, if the patient’s condition doesn’t meet severity thresholds, or if required pre-authorization was not obtained.

    - CPT 22551 – Arthrodesis, anterior interbody technique, including minimal discectomy to prepare interspace (other than for decompression); cervical below C2
    - Why It May Be Denied
    : Insurers often require extensive documentation of conservative measures (e.g., physical therapy, injections) before approving spinal fusion surgery. They may also question the appropriateness of the level(s) fused.

  • Cardiology


    - CPT 92928 – Percutaneous transcatheter placement of intracoronary stent(s), with coronary angioplasty when performed; single major coronary artery or branch
    - Why It May Be Denied
    : Insurers may question necessity if there’s incomplete proof of significant coronary artery disease, lack of prior medical management, or missing supporting diagnostic results.

    - CPT 93306 – Echocardiography, transthoracic, real-time with image documentation (2D), includes M-mode recording, complete
    - Why It May Be Denied
    : Denials may stem from insufficient justification (e.g., no clear indication of cardiac dysfunction), or payers may consider repeat echoes unnecessary within a short interval without new clinical findings.

  • Radiology & Imaging


    - CPT 70553 – Magnetic resonance imaging (MRI) of the brain (including brain stem); without and with contrast material
    - Why It May Be Denied
    : High-cost imaging is subject to stricter utilization review; payers may require prior authorization or deny if the clinical indication isn’t well-documented.

    - CPT 73721 – Magnetic resonance imaging (MRI) of any joint of lower extremity; without contrast material
    - Why It May Be Denied
    : May be deemed not medically necessary if conservative treatments weren’t attempted first, or if the symptoms do not match the diagnostic approach for suspected pathology.

FAQ

What is Substrate?
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Substrate is an AI company helping healthcare providers get paid what they've earned. We use AI and AI agents to handle tasks that a biller would otherwise do.
How do Substrate's agents operate?
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Substrate's AI Agents securely log into your EMR, practice management system, and your payor portals to retrieve claims data on your behalf. Substrate works with several leading EMRs including AdvancedMD, Practicefusion and more
What is a no response claim?
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A "no response claim" refers to a situation where an insurance company or claims administrator fails to respond to a submitted claim within the required timeframe. No response claims can also happen when a payor has an update on a claim in the payor portal, or that they send via paper, but does not result in an EOB or ERA being sent electronically. No response claims are frustrating because they add delays to a provider getting paid or a biller working that denial.
Is Substrate suitable for any provider?
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Yes - Substrate can work with both outpatient and inpatient practices. Substrate does not work for pharmacy, dental, or labs.
How does Substrate's claims monitoring work?
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Substrate's claims monitoring solution is very straightforward:1. First, a practice will define which claims they want monitored. This can be set up as a report that runs daily or weekly, or provided on an ad hoc basis.2. Next, Substrate maps each claim to the appropriate portal, logs in to the portal and looks for the claim3. Third, Substrate pulls the latest status of each claim from the payor portal, and surfaces it in the Substrate dashboard.4. Lastly, a practice can choose where to push the data; to the dashboard, to the practice management system, or even to a spreadsheet.
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